Production of Biologically Derived Small Molecule Regulatory Starting Materials and/or Active Pharmaceutical Ingredients at Commercial Scale

Through these BioMaP-Consortium awards, ASPR IBMSC is partnering with the awardees listed below to develop a biological design-build-test cycle for the production of small molecule drug substances at commercial scale. This supports ASPR IBMSC’s broader long-term goal of developing and commercializing infrastructure that will be accessible to a broad community of Users for the purpose of producing drug substances, creating a new manufacturing paradigm that can be competitive in the global market and to onshore drug production.

A Next-Generation Biomanufacturing Platform for Resilient, Agile, and Domestic Production of Critical Drug Substances

Project Details

Member Organization: 
Antheia, Inc.

Award Date: 
07/15/2024

Award Ceiling (Base period):
$11,089,240

Project Duration: 
24 months

Solicitation Number:
RPP 24-01-Small Molecule

CoMPASS: Continuous BioManufacturing Process Analysis for Scaling API Synthesis

Project Details

Member Organization: 
Capra Biosciences, Inc.

Award Date: 
07/12/2024

Award Ceiling (Base period):
$7,499,615

Project Duration: 
24 Months

Solicitation Number:
RPP 24-01-Small Molecule

Leveraging Amyris’s proven R&D, scale-up, and manufacturing platform for bioproduction of small molecule drugs and intermediates

Project Details

Member Organization: 
Amyris, Inc.

Award Date: 
09/24/2024

Award Ceiling (Base period):
$12,325,400

Project Duration: 
24 months

Solicitation Number:
RPP 24-01-Small Molecule